Problems with Beta Adrenergic Blocking Drugs and other Antihypertensive Drugs

Advantages and disadvantages of beta-adrenergic blocking drugs in hypertension.

This paper reviews the role of beta-adrenergic blocking drugs in the treatment of hypertension. A significant proportion of patients presenting with mild or moderate hypertension will respond to general measures and do not require specific drug therapy. Of the remaining patients, some will respond to treatment with a thiazide diuretic alone, and those with severe grades of hypertension will req...

Hypertension, heart failure, and beta-adrenergic blocking drugs.

eta-adrenergic receptor blocking drugs have arguably preented or delayed more deaths in patients with established eart disease that any other class of pharmaceutical agent 1). These drugs fundamentally alter the clinical course of atients with heart failure and a reduced left ventricular jection fraction, improving left ventricular performance, eversing left ventricular remodeling, and reducing...

Beta-adrenergic blocking drugs in the treatment of hypertension.

The reduction in blood pressure seen with the use of beta-blocking drugs was an unexpected finding. Initially there was resistance to their use as the reduction of cardiac output and increase in peripheral resistance from beta-blockade was considered an undesirable pharmacological action for a drug in the treatment of hypertension. However, beta-blockers have now become established in the treat...

Interactions between antihypertensive agents and other drugs.

Drug interactions in patients on long-term oral anticoagulant and antihypertensive adrenergic neuron-blocking drugs.

The occurrence of drug interactions was studied in outpatients on anticoagulant or adrenergic neuron-blocking drugs. In the anticoagulant group (254 patients) a theoretical potential drug interaction with warfarin was noted in 33% of patients with drugs supplied by prescription and in 30% of patients with drugs taken as self-medication, though a probable adverse drug interaction was documented ...